Tag: biology

The diagnosis and treatment of rare diseases have long been a daunting challenge due to their complex and often undefined nature. However, with recent advancements in technology, specifically in the realm of genomics, whole genome sequencing (WGS) has emerged as …

What is cystic fibrosis? Cystic fibrosis (CF) is a rare genetic disorder that affects the lungs, digestive system, and other organs. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a protein that …

Introduction to Directed Evolution Directed evolution is a cyclic process, which recreates the natural evolutionary process. It involves the generation of gene libraries based on one or more parent gene sequences. Through random mutagenesis and recombination, a large number of …

Introduction to De Novo Protein Design De novo approach, also known as the inverse protein folding problem, involves designing proteins from scratch. De novo design has proven a powerful method for understanding protein folding and function, and for mimicking or even bettering the properties of …